[1]林昌稳 罗世春 蒋 晶 熊 坚 昝 燕 姚蘅珊 谭姝文 乔 赟.基于数据挖掘技术探析中医慢性鼻炎处方用药规律[J].大众科技,2022,24(11):72-77.
 Exploration on the Prescription Rules of Chronic Rhinitis in Traditional Chinese Medicine Based on Data Mining Technology[J].Popular Science & Technology,2022,24(11):72-77.
点击复制

基于数据挖掘技术探析中医慢性鼻炎 处方用药规律()
分享到:

《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
24
期数:
2022年11
页码:
72-77
栏目:
医药与卫生
出版日期:
2022-11-20

文章信息/Info

Title:
Exploration on the Prescription Rules of Chronic Rhinitis in Traditional Chinese Medicine Based on Data Mining Technology
作者:
林昌稳1 罗世春2 蒋 晶1 熊 坚2 昝 燕1 姚蘅珊1 谭姝文1 乔 赟1 
(1.广西中医药大学,广西 南宁 530001;2.成都中医药大学,四川 成都 610075)
关键词:
慢性鼻炎中医数据挖掘用药规律中药
Keywords:
chronic rhinitis traditional Chinese medicine data mining prescription rules Chinese medicine
文献标志码:
A
摘要:
目的:基于数据挖掘技术,探究在中医药理论体系中治疗慢性鼻炎的处方用药规律,从而可以为慢性鼻炎在临床治疗的遣方用药方面提供一定的理论依据。方法:中国期刊全文数据库(CNKI)、万方数据库(Wanfang Data)和维普中文科技期刊全文数据库(VIP)将被全面检索作为数据文献来源,检索时间区间为建库至2020年6月,收集中医药治疗慢性鼻炎的方药文献,对文献处方运用Microsoft Excel 2013进行数据统计,建立处方数据库,进行数据分析计算则应用SPSS 17.0与SPSS Modeler 14.1,找出其核心药物、方组,挖掘中医慢性鼻炎处方用药规律。结果:共筛选出相关处方570条;药物使用频次最多的是辛夷,其次为苍耳子,之后为白芷;药性以温性药物使用最多,其后依次为微寒、平;药味以辛味最为常用,其次味苦、甘;归经以手太阴肺经为最;药物归类以解表药使用最多,清热药次之,其次为补虚药等其他药物;聚类分析大致可得到8个有效聚类群集,关联规则分析共发现597条规则,其中发现的强关联药物组有:苍耳子→辛夷、白芷+辛夷→苍耳子、甘草+苍耳子+辛夷→白芷等。结论:通过数据挖掘技术发现中医治疗慢性鼻炎方药的应用存在一定的规律,临床用药较为广泛,以辛夷、苍耳子、白芷等为核心药物,辛温解表法为治疗慢性鼻炎的基本治法,兼以甘温扶正,核心关联组合与聚类集群可直接配伍组成相关方药处方,为临床应用提供参考和指导。
Abstract:
Objective: To explore the prescription rules of chronic rhinitis in the theoretical system of traditional Chinese medicine based on data mining technology, so as to provide a certain theoretical basis for the prescription medication of chronic rhinitis in clinical treatment. Methods: The Chinese Journal Full-text Database (CNKI), Wanfang Data and VIP Chinese Science and Technology Journal Full-text Database (VIP) will be comprehensively searched as data sources. The retrieval time period is from the establishment of the database to June 2020, and the prescriptions of traditional Chinese medicine in the treatment of chronic rhinitis will be collected. Microsoft Excel 2013 was used for data statistics and prescription database was established. SPSS 17.0 and SPSS Modeler 14.1 were used for data analysis and calculation to find out the core drugs and prescription groups, and explore the prescription medication rules of chronic rhinitis in traditional Chinese medicine. Results: A total of 570 prescriptions were screened out. The most frequently used drug was magnolia, followed by xanthium sibiricum, followed by angelica dahurica warm drugs were used most frequently, followed by slightly cold and mild drugs the most commonly used medicine was bitter, followed by bitter and sweet the lung meridian of hand taiyin was the most important meridian tropism the most commonly used drugs were surface relieving drugs, followed by antipyretic drugs, followed by tonic drugs and other drugs cluster analysis can roughly get 8 effective cluster, and association rule analysis found 597 rules, among which the strong association drug groups found are: Xanthium sibiricum → magnolia, Angelica dahurica+magnolia → Xanthium sibiricum, licorice+Xanthium sibiricum+magnolia → Angelica dahurica, etc. Conclusion: Through data mining technology, it is found that there are certain rules in the application of traditional Chinese medicine prescriptions for chronic rhinitis. The clinical medication is relatively extensive, with magnolia, xanthium sibiricum and angelica dahurica as the core drugs, and the method of relieving exterior symptoms with pungent temperature as the basic treatment for chronic rhinitis, and also with the method of sweet and warm, the core association combination and cluster can be directly combined to form relevant prescriptions, providing reference and guidance for clinical application.

参考文献/References:

[1] YEN H R, SUN M F, LIN C L, et al. Adjunctive traditional Chinese medicine therapy for patients with chronic rhinosinusitis: A population-based study[J]. International Forum of Allergy and Rhinology, 2015, 5(3): 240-246. [2] 王景阳,白丽君,陈光艳,等. 裴正学教授治疗慢性鼻炎及鼻窦炎经验[J]. 中医研究,2019,32(3): 51-53. [3] 安立,王才友,王才会. 中西医结合治疗慢性鼻炎的实效性探究[J]. 中国医药指南,2014,12(36): 255,259. [4] 赵丽,苗兰兰. 中医治疗慢性鼻炎临床研究进展[J]. 光明中医,2019,34(16): 2583-2586. [5] 刘娇媚. 中医治疗慢性鼻炎临床疗效观察[J]. 四川中医,2015,33(4): 158-159. [6] 李颖. 辛芷熏鼻散治疗肺经蕴热型慢性单纯性鼻炎的疗效观察[J]. 中医临床研究,2021,13(29): 124-126. [7] 吴小燕. 揿针结合局部通窍推拿法治疗肺脾气虚证慢性鼻炎的效果研究[J]. 中国全科医学,2020,23(S1): 210-213. [8] 徐鹏昌. 鼻三针联合董氏奇穴埋线法治疗慢性鼻炎的临床观察[J]. 中国民间疗法,2022,30(1): 42-44. [9] 徐巾贺,朱玲,吴飞虎. 新吾针联合鼻三针治疗慢性鼻炎气滞血瘀证临床观察[J]. 亚太传统医药,2020,16(2): 114-116. [10] 赵阳,于彦,李建瑞,等. 祛风通窍方联合低温等离子射频消融术治疗慢性鼻炎51例[J]. 陕西中医,2013,34(7): 855-856. [11] 田霜. 加用中医辨证治疗慢性单纯性鼻炎疗效观察[J]. 广西中医药,2013,36(2): 47-48. [12] 宋卫红. 桂枝加附子汤玉屏风散治疗慢性鼻炎120例[J]. 陕西中医,2013,34(2): 194-196. [13] YIN Z, GENG G, XU G, et al. Acupuncture methods for allergic rhinitis: A systematic review and bayesian meta-analysis of randomized controlled trials[J]. Chinese Medicine, 2020, 15: 109. [14] 熊坚,陶庆锋,刘致含,等. 基于数据挖掘技术探析针灸治疗后循环缺血性眩晕选穴规律[J]. 亚太传统医药,2021,17(9): 129-134. [15] 李国祥,胡镜清,潘秋霞,等. 基于数据挖掘分析清代胸痹症状及方剂特征[J]. 世界科学技术-中医药现代化,2021,23(6): 1895-1901. [16] 雷黄伟,徐佳君,杨朝阳,等. 基于数据驱动的名老中医学术经验智能化传承研究[J]. 中国中医基础医学杂志,2021,27(7): 1111-1113,1144. [17] 罗世春,赖鹏,熊坚,等. 基于数据挖掘技术探析中医乌发专利方药规律[J]. 中国民族民间医药,2021,30(13): 20-28. [18] 邓凯烽,宁恒,陆惠玲,等. 基于现代数据挖掘技术分析中医外治法治疗膝骨关节炎的用药规律[J]. 中国中医基础医学杂志,2021,27(5): 796-801. [19] 贺雅琪,孙定乾,段骄,等. 基于数据挖掘的冼绍祥治疗慢性稳定性冠心病用药规律研究[J]. 中国中医基础医学杂志,2020,26(2): 209-211,216. [20] 国家药典委员会. 中华人民共和国药典: 一部[M]. 北京:中国医药科技出版社,2015. [21] 周祯祥,唐德才. 中药学[M]. 北京: 中国中医药出版社,2016. [22] TIOTIU A, NOVAKOVA P, GUILLERMO G, et al. Management of adult asthma and chronic rhinitis as one airway disease[J]. Expert Review of Respiratory Medicine 2021, 15(9): 1135-1147. [23] 林向华,王英,肖旺贤,等. Th17细胞在慢性鼻炎常见病中的表达及意义[J]. 中国卫生检验杂志,2015,25(7): 913-916. [24] 王嘉,高亚娜,田东倩,等. 慢性鼻病中乏氧诱导因子-1与5-脂加氧酶的表达及意义[J]. 临床误诊误治,2021,34(4): 97-102. [25] 张仲林,钟玲,凌保东,等. 玉屏风散调控变应性鼻炎大鼠IL-6、TNF-α活性的实验研究[J]. 中成药,2014,36(9): 1804-1808. [26] 张波,郭燕冰,许继宗,等. 变应性鼻炎患者血清褪黑素、一氧化氮水平的季节测定及临床意义[J]. 中国医刊,2015,50(4): 80-83.

相似文献/References:

[1]李文芳 徐昌荣 乔赟.哮喘的中医防治概况[J].大众科技,2014,16(07):138.
 Prevention and treatment of asthma medicine overview[J].Popular Science & Technology,2014,16(11):138.
[2]李伟茜 唐 农 王晋平 莫斯思.血管性痴呆的中医病因病机研究进展[J].大众科技,2015,15(03):105.
[3]林翠英,林 扬,王艳娇,等.灸法治疗肝硬化腹水研究进展[J].大众科技,2019,21(09):69.
 Research Progress of Moxibustion in the Treatment of Ascites due to Liver Cirrhosis[J].Popular Science & Technology,2019,21(11):69.
[4]张 北,梁爱武.中医治疗慢性阻塞性肺疾病稳定期的研究进展[J].大众科技,2019,21(10):53.
 Research Rrogress in the Treatment of Chronic Obstructive Pulmonary Disease by Traditional Chinese Medicine[J].Popular Science & Technology,2019,21(11):53.
[5]申永艳,何贵新2,肖婷,等.不稳定型心绞痛中西医结合诊疗新进展[J].大众科技,2019,21(11):51.
 New Progress in Treatment of Unstable Angina Pectoris with Integrated Traditional Chinese and Western Medicine[J].Popular Science & Technology,2019,21(11):51.
[6]陈 萍 方桂玉 王梓霞 钟 建.中医药治疗狼疮性肾炎的研究进展[J].大众科技,2021,23(9):43.
 Research Progress on Treatment of Lupus Nephritis withTraditional Chinese Medicine[J].Popular Science & Technology,2021,23(11):43.
[7]何晓微 杨瑜善 马兴宇 张青槐.试论壮医腹诊与中医腹诊的异同[J].大众科技,2018,20(07):94.
 Discussion on the Similarities and Differences between Abdominal Diagnosis of Zhuang Medicine and Traditional Chinese Medicine[J].Popular Science & Technology,2018,20(11):94.
[8]彭文清,吴新贵.针灸治疗膝骨性关节炎的文献综述[J].大众科技,2019,21(12):75.
 The Literature Review of Acupuncture Therapy for Knee Osteoarthritis[J].Popular Science & Technology,2019,21(11):75.
[9]汪 超.PBL-案例式教学模式在中医教学中的应用探索[J].大众科技,2022,24(08):151.
 Application and Exploration of PBL Case-Based Teaching Mode in Traditional Chinese Medicine Teaching[J].Popular Science & Technology,2022,24(11):151.
[10]杜小华 黄映转 刘乔伟 刘运珠 梁睿智.中医治疗卵巢储备功能减退的临床研究进展[J].大众科技,2022,24(09):138.
 Clinical Research Progress of Traditional Chinese Medicine in the Treatment of Decreased Ovarian Reserve[J].Popular Science & Technology,2022,24(11):138.

备注/Memo

备注/Memo:
【收稿日期】2022-09-16 【基金项目】广西自然科学基金(2020GXNSFAA297021);广西壮族自治区大学生创新创业训练计划项目(XQJ21098);广西中医药大学大学生科研训练项目(2021DXS15、2020DXS18);广西中医药大学大学生创新创业训练计划项目(202010600193);广西中医药大学·一方制药大学生科技创新项目(2021DXS45)。 【作者简介】林昌稳(1999-),男,广东茂名人,广西中医药大学学生,研究方向为中药方剂临床用药规律研究。 【通信作者】乔赟(1965-),男,湖南东安人,广西中医药大学教授,医学博士,研究生导师,研究方向为针灸防治哮喘的临床与实验研究。
更新日期/Last Update: 2023-03-09