[1]黄凤积　张远景　农建平　莫彬杰　潘志良　董文兰.补肾化痰法联合达英-35治疗多囊卵巢综合症的Meta分析[J].大众科技,2021,23(11):53-56.
　Meta Analysis of Kidney-Tonifying and Phlegm-Reducing Therapy Combined with Dayiny-35 in the Treatment of Polycystic Ovarian Syndrome[J].Popular Science & Technology,2021,23(11):53-56.
点击复制

补肾化痰法联合达英-35治疗多囊卵巢综合症的Meta分析()
分享到：

《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
23
期数:
2021年11
页码:
53-56
栏目:
医药与卫生
出版日期:
2021-11-20

文章信息/Info

Title:
Meta Analysis of Kidney-Tonifying and Phlegm-Reducing Therapy Combined with Dayiny-35 in the Treatment of Polycystic Ovarian Syndrome
作者:
黄凤积1; 2　张远景1　农建平1　莫彬杰1　潘志良1　董文兰1　
（1.南宁长峰中医医院，广西 南宁 530000；2.广西中医药大学，广西 南宁 530000）
关键词:
多囊卵巢综合征; 补肾化痰; 达英-35; Meta分析
Keywords:
polycystic ovary syndrome tonifying kidney and reducing phlegm Daying-35 Meta analysis
文献标志码:
A
摘要:
目的：采用Meta分析方法评价补肾化痰法联合达英-35治疗多囊卵巢综合征的有效性。方法：计算机检索CNKI、万方、维普、PubMed、Cochrane Library、Springer数据库中有关的补肾化痰法联合达英-35治疗多囊卵巢综合征的临床随机对照试验（RCT），检索年限从建库至2020年12月。由两名研究人员独立进行文献的检索和筛选，采用Cochrane协作网综述手册评估文献质量、RevMan5.3软件进行Meta分析。结果：最终有14篇文献共1041例RCT进入研究，Meta分析结果提示，在补肾化痰法联合达英-35治疗多囊卵巢综合征上，患者临床疗效、中医证候疗效、排卵率、妊娠率、月经改善、LH、FSH、T、E2等效果明显优于单纯使用西药组，差异有统计学意义（P<0.05）；但PRL和多毛评分疗效稍差，差异无统计学意义（P>0.05）。结论：补肾化痰法联合达英-35治疗多囊卵巢综合征疗效优于单纯使用达英-35，是临床治疗该病的最佳方法。
Abstract:
Objective: To evaluate the efficacy of kidney-tonifying and phlegm-reducing therapy combined with Daying-35 in the treatment of polycystic ovary syndrome by Meta analysis. Methods: Randomized controlled trials (RCTs) related to kidney-tonifying and phutm-reducing method combined with Daying-35 in the treatment of polycystic ovary syndrome were searched from CNKI, Wanfang, Weip, PubMed, Cochrane Library and Springer database, and the retrieval period was from database establishment to December 2020. Literature retrieval and screening were conducted independently by two researchers, and literature quality was assessed using the Cochrane collabrador review manual, and Meta-analysis was performed by using RevMan5.3 software. Results: Finally, a total of 1041 RCTs in 14 literatures were included in the study. Meta analysis results indicated that in the treatment of polycystic ovary syndrome by Kidney-tonifying and phlegm-reducing method combined with Daying-35, the clinical efficacy, TCM syndrome efficacy, ovulation rate, pregnancy rate, menstruation improvement, LH, FSH, T, E2 and other effects were significantly better than those of the western medicine group alone. The difference was statistically significant(P<0.05) however, the efficacy of PRL and hiriness score was slightly worse, and the difference was not statistically significant(P<0.05). Conclusion: Kidney-tonifying and phlegm-reducing method combined with Daying-35 is better than Daying-35 alone in the treatment of polycystic ovary syndrome, and is the best method for clinical treatment of the disease.

参考文献/References:

[1]　钱易，马翔. 多囊卵巢综合征诊断标准解读[J]. 中国实用妇科与产科杂志，2019(3): 264-267. [2]　叶艳，卢苏，陆葳. 卢苏教授诊治青春期多囊卵巢综合征经验探析[J]. 浙江中医药大学学报，2018，42(2): 138-141. [3]　Rotterdam E S, ASRM-Sponsored P C. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)[J]. Human Reproduction, 2004, 19(1): 41-47. [4]　张娟. 补肾化痰方联合西医治疗PCOS临床疗效及对内分泌指标的影响研究[J]. 亚太传统医药，2018(4): 177-179. [5]　雷小娟，孙建荣. 补肾化痰汤联合炔雌醇环丙孕酮片对多囊卵巢综合征患者生殖激素水平的影响[J]. 中国民间疗法，2019(16): 34-35. [6]　刘欣.补肾化痰助孕方联合达英-35治疗多囊卵巢综合征的临床效果观察[J]. 中国妇幼保健，2017，32(8): 1649-1651. [7]　甘瑾.补肾祛瘀化痰方联合达英-35治疗多囊卵巢综合征的疗效研究[J]. 中医药学报，2017，45(5): 85-87 [8]　郝焕妮. 化痰补肾汤联合达英-35治疗多囊卵巢综合征所致不孕30例[J]. 河南中医，2010. 30(8): 783-784. [9]　陈映霞，靳海娥，李秀旎. 益肾化痰调经方联合达英-35治疗多囊卵巢综合征60例[J]. 中国中医药科技， 2019，26(3): 463-465. [10] 张金菊，林寒梅. 中药联合达因-35治疗多囊卵巢综合征的临床观察[J]. 广西中医学院学报，2012，15(2): 16-17. [11] 梅菊丽. 补肾化痰法联合达英-35治疗肾虚痰阻型多囊卵巢综合征高雄激素血症的临床研究[D]. 南京: 南京中医药大学，2010. [12] 姚凤伟. 补肾祛痰法联合达英-35治疗多囊卵巢综合征高睾酮血症的临床研究[D]. 哈尔滨: 黑龙江中医药大学，2011. [13] 周正. 达英-35与中药补肾化痰方序贯治疗肾虚痰湿型多囊卵巢综合征的临床研究[D]. 杭州: 浙江中医药大学，2014. [14] 汤星月. 养精导痰汤联合达英-35治疗肾虚痰湿型多囊卵巢综合征的临床观察[D]. 合肥: 安徽中医药大学，2018. [15] 揣艳飞. 补肾化痰方联合达英-35对肾虚痰湿型PCOS卵巢超声参数的影响[D]. 郑州: 河南中医药大学，2016. [16] 刘艳与段育华. 达英-35联合补肾化痰调经汤治疗肾虚痰湿型多囊卵巢综合征致月经后期[J]. 实用妇科内分泌电子杂志，2019，6(21): 72-73. [17] 郭晖，陈玲玲，何嘏娜，等. 补肾化痰方对多囊卵巢综合征患者MMPs及IGFBP-1表达变化的影响[J]. 福建医药杂志，2017，39(3): 107-109. [18] 马捷，刘莹，钟来平，等. Jadad量表与Cochrane偏倚风险评估工具在随机对照试验质量评价中的应用与比较[J]. 中国口腔颌面外科杂志，2012，10(5): 417-422. [19] 饶龙，朱虹丽. 从脾肾论治多囊卵巢综合征的研究进展[J]. 中医文献杂志，2019，37(2): 70-72.

相似文献/References:

[1]魏倍倍 林寒梅.脾虚痰湿型多囊卵巢综合征治疗现状研究[J].大众科技,2019,21(01):57.
　Study on the Treatment of Spleen-deficiency and Phlegm-damp Type Polycystic Ovary Syndrome[J].Popular Science & Technology,2019,21(11):57.
[2]刘 英,吴媛媛,罗志娟.苍附导痰丸加减联合达英 35 治疗脾虚痰湿证多囊卵巢综合征的临床观察[J].大众科技,2019,21(04):78.
　Clinical Observation of Modified Cang Fu Dao Tan Wan Combined with Diane-35in the Treatment of Polycystic Ovary Syndrome of Spleen-deficientPhlegm-dampness Syndrome[J].Popular Science & Technology,2019,21(11):78.
[3]刘 英,韦思尊,钟 洁.雷火灸联合仿生物电刺激对肥胖型多囊卵巢综合征患者代谢的影响[J].大众科技,2019,21(07):82.
　Effect of Thunder Fire Moxibustion Combined with Biomimetic ElectricalStimulation on the Metabolism of Obese Polycystic Ovary Syndrome Patients[J].Popular Science & Technology,2019,21(11):82.
[4]李 珊.多囊卵巢综合征的发病机制及中西医疗法研究进展[J].大众科技,2021,23(1):71.
　Advances in the Pathogenesis of Polycystic Ovary Syndrome and the Treatment of Traditional Chinese and Western Medicine[J].Popular Science & Technology,2021,23(11):71.

备注/Memo

备注/Memo:
【收稿日期】2021-09-10 【作者简介】黄凤积（1992－），女，南宁长峰中医医院执业医师，中医师，从事中医科医师工作。
更新日期/Last Update: 2022-02-14