[1]邹　俊　劳晓洁　赵　蕊　梁振国　陈茂伟.HIV/AIDS患者肠道菌群变化研究[J].大众科技,2021,23(1):44-47.
　Study on Changes of Intestinal Flora in HIV/AIDS Patients[J].Popular Science & Technology,2021,23(1):44-47.
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HIV/AIDS患者肠道菌群变化研究()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
23
期数:
2021年1
页码:
44-47
栏目:
医药与卫生
出版日期:
2021-01-20

文章信息/Info

Title:
Study on Changes of Intestinal Flora in HIV/AIDS Patients
作者:
邹　俊1　劳晓洁2　赵　蕊1　梁振国2　陈茂伟3
（1.南宁市第四人民医院（广西艾滋病临床治疗中心），广西 南宁 530023； 2.广西医科大学，广西 南宁530199；3.广西医科大学附属武鸣医院，广西 南宁530199）
关键词:
肠道菌群; 艾滋病; HIV
Keywords:
intestinal flora;  AIDS;  HIV
文献标志码:
A
摘要:
艾滋病是严重危害人类健康和生命的重大疾病，艾滋病病毒感染会破坏人体肠道黏膜屏障，打破肠道菌群的平衡。文章对比HIV感染者与正常人肠道菌群之间的区别，为临床诊疗提供参考依据，进而为寻求机制学说提供科研思路。
Abstract:
AIDS is a major disease that seriously endangers human health and life. HIV infection will destroy the human intestinal mucosal barrier and break the balance of intestinal flora. This paper compares the differences between the intestinal flora of HIV infected people and normal people, so as to provide reference for clinical diagnosis and treatment, and provide scientific research ideas for seeking mechanism theory.

参考文献/References:

[1]　Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins[J]. Nature, 2009. 457(7228): 480-484. [2]　Sculier D, Calmy A. What’s new in HIV in 2014[J]. RevMed Suisse, 2015, 11(456/457): 148-152. [3]　Epple H J, Schneider T, Troeger H et al. Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients[J]. Gut, 2009, 58: 220, 7. [4]　Canipe A, Chidumayo T, Blevins M, et al. A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy[J]. BMC Infectious Diseases, 2014, 14: 521. [5]　Rosero O, Kovács T, Onody P, et al. Bakteriális transzlokáció: rés a pajzson [Bacterial translocation: gap in the shield][J]. Orv Hetil, 2014, 155(8): 304-312. [6]　Fitzgerald F, Harris K, Doyle R, et al. Short communication: Evidence that microbial translocation occurs in HIV-infected children in the United Kingdom[J]. AIDS Research and Human Retroviruses, 2013, 29(12): 1589-1593. [7]　Nowak P, Troseid M, Avershina E, et al. Gut microbiota diversity predicts immune status in HIV-1 infection. AIDS. 2015, 29(18): 2409-2418. [8]　Noguera-Julian M, Rocafort M, Guillén Y, et al. Gut microbiota linked to sexual preference and HIV Infection[J]. EBioMedicine, 2016, 5: 135-146.

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备注/Memo

备注/Memo:
【收稿日期】2020-11-14 【基金项目】广西医科大学青年科学基金（GXMUYSF201742）。 【作者简介】邹俊（1984－），女，南宁市第四人民医院（广西艾滋病临床治疗中心）副主任医师，研究方向为传染病诊疗。 【通信作者】陈茂伟，广西医科大学附属武鸣医院副院长，研究方向为传染病学。
更新日期/Last Update: 2021-03-16