[1]黄明剑,潘朝锌,王庆高,等.丹参多酚酸盐联合生脉注射液对 STEMI 支架植入术后患者 ST 段回落及出血情况观察[J].大众科技,2020,22(06):92-94.
　Observation of ST Segment Retreat and Bleeding after STEMI Stent Implantationwith Salvia Miltiorrhiza Polyphenolates Combined with Shengmai Injection[J].Popular Science & Technology,2020,22(06):92-94.
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丹参多酚酸盐联合生脉注射液对 STEMI 支架植入术后患者 ST 段回落及出血情况观察()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
22
期数:
2020年06
页码:
92-94
栏目:
医药与卫生
出版日期:
2020-06-20

文章信息/Info

Title:
Observation of ST Segment Retreat and Bleeding after STEMI Stent Implantationwith Salvia Miltiorrhiza Polyphenolates Combined with Shengmai Injection
作者:
黄明剑;  潘朝锌;  王庆高;  吴万里;  庞 延
（广西中医药大学第一附属医院，广西 南宁 530023）
关键词:
急性 ST 段抬高型心肌梗死; 急诊冠脉介入术; 丹参多酚酸盐; 生脉注射液; 疗效
Keywords:
ST elevation myocardial infarction(STEMI);  emergency coronary intervention;  salvia polyphenolate;  Shengmaiinjections;  therapeutic effect
文献标志码:
A
摘要:
目的：探讨丹参多酚酸盐联合生脉注射液对急性 ST 段抬高型心肌梗死（STEMI）支架植入术后患者 ST 段回落及出血情况。方法：选择 2016 年 1 月到 2018 年 12 月广西中医药大学第一附属医院行急诊 PCI 后的 STEMI 患者，分为观察组和对照组，每组 30 例，观察组在常规西药治疗基础上加用丹参多酚酸盐联合生脉注射液治疗 7 天，观察术后 24h 心电图 ST 段回落情况及 7 天内出血情况，同时对比治疗前后中医证候积分及中医证候疗效。结果：观察组在常规西医治疗基础上加用丹参多酚酸盐联合生脉注射液能够明显提高 ST 段回落幅度及 ST 段回落发生率（P＜0.05），且并未增加出血事件发生率（P＞0.05）；观察组较对照组明显改善胸闷、胸痛、气短、心悸症状，且总有效率优于对照组（P＜0.05）。结论：丹参多酚酸盐联合生脉注射液联合西医常规药物治疗能够更有效改善 PCI 术后 STEMI 患者心肌再灌注以及临床症状，优于对照组。
Abstract:
Objective: To investigate the effect of salvianolate combined with Shengmai Injection on ST segment depression andbleeding in patients with acute ST segment elevation myocardial infarction (STEMI) after stent implantation. Methods: Patients withSTEMI after emergency PCI in the First Affiliated Hospital of Guangxi University of traditional Chinese medicine from January 2016 toDecember 2018 were selected and divided into observation group and control group, with 30 cases in each group. The observation groupwas treated with salvianolate combined with Shengmai injection for 7 days on the basis of conventional western medicine treatment. TheST segment depression in 24 hours after operation and the bleeding within 7 days were observed. At the same time, TCM syndrome scoreand TCM syndrome efficacy before and after treatment were compared. Results: On the basis of conventional western medicine treatment,salvianolate combined with Shengmai injection in the observation group could significantly improve the range and incidence of STsegment depression (P<0.05), and did not increase the incidence of bleeding events (P>0.05); compared with the control group, theobservation group significantly improved the symptoms of chest tightness, chest pain, shortness of breath and palpitation, and the totaleffective rate was better than that of the control group (P<0.05). Conclusions: Salvianolate combined with Shengmai injection combinedwith conventional western medicine can effectively improve myocardial reperfusion and clinical symptoms of STEMI patients after PCI,which is better than that of the control group.

参考文献/References:

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备注/Memo

备注/Memo:
【收稿日期】2020-05-08【作者简介】黄明剑（1981－），男，广西中医药大学第一附属医院心血管科副主任医师，硕士研究生，研究方向为心血管疾病介入及中西医结合治疗。
更新日期/Last Update: 2020-08-05