[1]黄景彬 梁 健 赵晓芳 韦思尊 杨柳山 张 赋 范 悦.先天性心脏病的分子机制研究进展[J].大众科技,,():98.
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先天性心脏病的分子机制研究进展
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
期数:
201403期
页码:
98
栏目:
医药与卫生
出版日期:

文章信息/Info

Title:
Progress in research on molecular mechanisms of congenital heart disease
文章编号:
1008-1151(2014)03-0098-05
作者:
黄景彬 梁 健 赵晓芳 韦思尊 杨柳山 张 赋 范 悦
(广西中医药大学附属瑞康医院,广西 南宁 530011)
关键词:
心脏发育先天性心脏病分子机制
Keywords:
Cardiac development congenital heart defects molecular mechanisms
分类号:
R54
文献标志码:
A
摘要:
先天性心脏病是出生缺陷最常见的畸形,其病因仍不清楚。分子遗传学、发育生物学的进展,发现了许多和心脏 发育有关的基因。先天性心脏病(CHD)是发育缺陷导致的畸形,其分子机制很复杂。文章综述总结正常的心脏发育过程和概括 先天性心脏病相关基因通路,分析先天性心脏病的可能机制,并提出相应研究策略。
Abstract:
Congenital heart disease (CHD) is the most common type of birth defect. Despite the many advances in our understanding of cardiac development and many genes related to cardiac development identified, the fundamental etiology for the majority of cases of congenital heart disease remains unknown. This review summarizes normal cardiac development and outlines the recent discoveries of the genetic causes of congenital heart disease, and provides possible strategies for exploring it.

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相似文献/References:

[1]黄景彬 梁 健 赵晓芳 韦思尊 杨柳山 张 赋 范 悦.先天性心脏病的分子机制研究进展[J].大众科技,2014,16(03):98.

备注/Memo

备注/Memo:
【收稿日期】2014-01-08 【基金项目】本课题由国家自然基金(批准编号: 81360014)、广西科技攻关(批准编号: 2013BC26236)、广西卫生厅项目(批 准编号: GZPT13-27)、瑞康医院自然基金(批准编号: ZKZ201001)资助。 【作者简介】黄景彬(1974-),广西人,广西中医药大学附属瑞康医院医学博士,从事心胸外科的基础和临床研究和教育。
更新日期/Last Update: 1900-01-01