[1]吴丽萍 陈晓锋 王清碧 金 欣 邵天祥.基于肠道菌群探讨腹针治疗脑卒中后失眠的应用[J].大众科技,2023,25(3):118-121.
 Discussion on the Application of Abdominal Acupuncture in the Treatment of Insomnia after Stroke Based on Intestinal Flora[J].Popular Science & Technology,2023,25(3):118-121.
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基于肠道菌群探讨腹针治疗脑卒中后失眠的应用()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
25
期数:
2023年3
页码:
118-121
栏目:
医药与卫生
出版日期:
2023-03-20

文章信息/Info

Title:
Discussion on the Application of Abdominal Acupuncture in the Treatment of Insomnia after Stroke Based on Intestinal Flora
作者:
吴丽萍1 陈晓锋2 王清碧2 金 欣2 邵天祥1
(1.广西中医药大学研究生院,广西 南宁 530001;2.广西中医药大学附属瑞康医院,广西 南宁 530011)
关键词:
肠道菌群脑卒中后失眠腹针
Keywords:
intestinal flora insomnia after stroke abdominal acupuncture
文献标志码:
A
摘要:
脑卒中后失眠是脑卒中患者常见并发症,该病得不到及时有效的治疗不仅会影响患者的神经康复进程,甚至还可导致脑卒中的再次复发。脑卒中后失眠患者多存在肠道菌群中益生菌的减少、多样性的降低等肠道菌群紊乱现象,文章通过论述肠道菌群与脑卒中的联系,以及与脑卒中后失眠的发生发展关系,探讨腹针治疗脑卒中后失眠的理论依据与应用,以期为临床治疗和研究提供思路。
Abstract:
Insomnia after stroke is a common complication in the stroke patients, and without timely and effective treatment, it will not only affect the process of neurological rehabilitation, but also lead to recurrence of stroke. Most patients with insomnia after stroke have intestinal flora disorders such as the decrease of probiotics and the decrease of diversity in intestinal flora. This paper discusses the relationship between intestinal flora and stroke and the relationship between intestinal flora and occurrence and development of insomnia after stroke, to explore the theoretical basis and application of abdominal acupuncture in treating insomnia after stroke, so as to provide ideas for clinical treatment and research.

参考文献/References:

[1] FERRE A, RIBO M, RODRIGUEZ-LUNA D, et al. Strokes and their relationship with sleep and sleep disorders[J]. Neurologia, 2013. 28(2): 103-118.[2] McDERMOTT M, BROWN D L, CHERVIN R D. Sleep disorders and the risk of stroke[J]. Expert Review of Neurotherapeutics, 2018, 18(7): 523-531.[3] KIM S, JAZWINSKI S M. The gut microbiota and healthy aging: A mini-review[J]. Gerontology, 2018, 64(6): 513-520.[4] 李超华. 腹针治疗中风后失眠的临床观察[D]. 沈阳: 辽宁中医药大学,2015.[5] KOLOSKI N A, JONES M, KALANTAR J, et al. The brain--gut pathway in functional gastrointestinal disorders is bidirectional: A 12-year prospective population-based study[J]. Gut, 2012, 61(9): 1284-1290.[6] 田娜颖,吴硕琳,王春雪,等. 脑卒中后失眠患者的临床特点及危险因素分析[J]. 中国医刊,2018,53(9): 979-982.[7] 谢艳,刘志广. 脑卒中后睡眠障碍患者脑源性神经营养因子相关因素分析[J]. 实用心脑肺血管病杂志,2015,23(6): 61-63.[8] LI LJ, YANG Y, GUAN B Y, et al. Insomnia is associated with increased mortality in patients with first-ever stroke: a 6-year follow-up in a Chinese cohort study[J]. Stroke and Vascular Neurology, 2018, 3(4): 197-202.[9] LEPROULT R, COPINSCHI G, BUXTON O, et al. Sleep loss results in an elevation of cortisol levels the next evening[J]. Sleep, 1997, 20(10): 865-870.[10] CARLESSI A S, BORBA L A, ZUGNO A I, et al. Gut microbiota-brain axis in depression: The role of neuroinflammation[J]. European Journal of Neuroscience, 2021, 53(1): 222-235.[11] LIU R T, WALSH R, SHEEHAN A E. Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials[J]. Neuroscience and Biobehavioral Reviews,, 2019, 102: 13-23.[12] CEPEDA M S, KATZ E G, BLACHETER C. Microbiome-gut-brain axis: Probiotics and their association with depression[J]. Journal of Neuropsychiatry and Clinical Neurosciences, 2017, 29(1): 39-44.[13] ROGERS G B, KEATING D J, YOUNG R L, et al. From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways[J]. Molecular Psychiatry, 2016, 21(6): 738-748.[14] KOREM T, ZEEVI D, SUEZ J, et al. Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples[J]. Science, 2015, 349(6252): 1101-1106.[15] LI N, WANG X, SUN C, et al. Change of intestinal microbiota in cerebral ischemic stroke patients[J]. BMC Microbiology, 2019, 19(1): 191.[16] 徐晓松,蔡祥胜,李瑞莹,等. 急性脑卒中患者肠道菌群研究[J]. 中国微生态学杂志,2022,34(5): 562-566.[17] SHARMA V, SHARMA V, SHAHJOUEI S, et al. At the intersection of gut microbiome and stroke: A systematic review of the literature[J]. Frontiers in Neurology, 2021, 12: 729399.[18] FU J, BONDER M J, CENIT M C, et al. The gut microbiome contributes to a substantial proportion of the variation in blood lipids[J]. Circulation Research, 2015, 117(9): 817-824.[19] 杨泽俊,王田田,尚宏伟,等. 肠道菌群代谢产物与脑-肠-骨髓轴在高血压调节中的作用[J]. 国际心血管病杂志,2021,48(1): 17-21.[20] SAAD M J, SANTOS A, PRADA P O. Linking gut microbiota and inflammation to obesity and insulin resistance[J]. Physiology, 2016, 31(4): 283-293.[21] SCHIERING C, WINCENT E, METIDJI A, et al. Feedback control of AHR signalling regulates intestinal immunity[J]. Nature, 2017, 542(7640): 242-245.[22] GE X, ZHENG L, ZHUANG R, et al. The gut microbial metabolite trimethylamine N-oxide and hypertension risk: A systematic review and dose-response Meta-analysis[J]. Advances in Nutrition, 2020, 11(1): 66-76.[23] SEN P, MOLONER-PEREZ A. Microbiota and sleep: awakening the gut feeling[J]. Trends In Molecular Medicine, 2021, 27(10): 935-945.[24] HUANG T T, LAI J B, DU Y L, et al. Current understanding of gut microbiota in mood disorders: An update of human studies[J]. Frontiers in Genetics, 2019, 10: 98.[25] DINAN T G, CRTAN J F. The Microbiome-gut-brain axis in health and disease[J]. Gastroenterology Clinics of North America, 2017, 46(1): 77-89.[26] Ganci M, Suleyman E, Butt H, et al. The role of the brain-gut-microbiota axis in psychology: The importance of considering gut microbiota in the development, perpetuation, and treatment of psychological disorders[J]. Brain and Behavior, 2019, 9(11): e01408.[27] 田甜,卢英,李武,等. 肠道菌群在脑卒中发病中的研究进展[J]. 医学研究杂志,2020,49(12): 24-27.[28] JACKSOB M L, BUTT H, BALL M, et al. Sleep quality and the treatment of intestinal microbiota imbalance in chronic fatigue syndrome: A pilot study[J]. Sleep Science, 2015, 8(3): 124-133.[29] KUROKAWA S, KISHIMOTO T, MIZUNO S, et al. The effect of fecal microbiota transplantation on psychiatric symptoms among patients with irritable bowel syndrome, functional diarrhea and functional constipation: An open-label observational study[J]. Journal of Affective Disorders, 2018, 235: 506-512.[30] 薄智云. 谈谈腹针疗法[J]. 中国针灸,2001(8): 27-29.[31] 郭亚雄,陈育忠,柳东杨,等. 腹针疗法促进胃切除术后胃肠蠕动67例疗效观察[J]. 新中医,2006(7): 68.[32] 徐振华,符文彬,薄智云. 从经络学说角度探讨腹针疗法的理论基础[J]. 针灸临床杂志,2011,27(6): 59-60.[33] 方继良,洪洋,王小玲,等. 运用fMRI观察电针关元及中脘穴相对特异性的脑功能网络[J]. 针刺研究,2011,36(5): 366-372.[34] 李虹,侯中伟,白玉兰,等. 近红外光成像技术研究电子艾灸的脑皮层效应[J]. 中国针灸,2010,30(11): 925-927.[35] 姬乐,陈晓锋,石丽华. fMRI指导腹针治疗对中风病人日常生活活动能力的影响[J]. 中西医结合心脑血管病杂志,2017,15(10): 1252-1254.[36] 王照钦,钟蕊,高崚,等. 针刺对帕金森病模型小鼠肠道菌群多样性的调节作用[J]. 中华中医药杂志,2020,35(5): 2265-2270.[37] 赵红霞,刘洪波,胡佳,等. 腹针联合康复训练对缺血性脑卒中患者肠道菌群及炎性因子的影响[J]. 中国病原生物学杂志,2021,16(10): 1211-1215.[38] 王叶青,洪敏,张凯娜,等. 观察薄氏腹针对脑卒中患者MMSE评分及血清D-乳酸、二胺氧化酶的影响[J]. 辽宁中医杂志,2019,46(9): 1958-1960.[39] 李玉龙. 腹针联合体针治疗心脾两虚型卒中后失眠的临床疗效观察[D]. 天津: 天津中医药大学,2021.[40] 刘雪影. 定神针结合腹针治疗中风后失眠症的疗效观察[D]. 广州: 广州中医药大学,2016.

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备注/Memo

备注/Memo:
【收稿日期】2022-09-14【基金项目】广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z20180875);广西中医药大学2019-2021年广西一流学科建设开放课题青年基金项目(2019XK177);广西中医药大学研究生教育创新计划项目(CXJ2021104)。【作者简介】吴丽萍(1994-),女,广西防城港人,广西中医药大学研究生院在读硕士研究生,研究方向为康复医学及神经内科的中西医结合临床研究。【通信作者】陈晓锋(1972-),男,广西中医药大学附属瑞康医院主任医师,教授,硕士研究生导师,研究方向为康复医学及神经内科的中西医结合临床研究。
更新日期/Last Update: 2023-05-31