[1]胡晓玲 陈斯宁 陆 珏.中性粒细胞弹性蛋白酶与慢性阻塞性肺疾病关系的研究进展[J].大众科技,2023,25(1):123-126.
　Research Progress on the Relationship between Neutrophil Elastase and Chronic Obstructive Pulmonary Disease[J].Popular Science & Technology,2023,25(1):123-126.
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中性粒细胞弹性蛋白酶与慢性阻塞性肺疾病关系的研究进展()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
25
期数:
2023年1
页码:
123-126
栏目:
医药与卫生
出版日期:
2023-01-20

文章信息/Info

Title:
Research Progress on the Relationship between Neutrophil Elastase and Chronic Obstructive Pulmonary Disease
作者:
胡晓玲1 陈斯宁2 陆 珏1　
（1.广西中医药大学，广西 南宁 530001； 2.广西中医药大学附属瑞康医院，广西 南宁 530001）
关键词:
中性粒细胞弹性蛋白酶; 慢性阻塞性肺疾病; 相关性
Keywords:
neutrophil elastase chronic obstructive puimonary disease correlation
文献标志码:
A
摘要:
慢性阻塞性肺疾病是一种常见且多发的呼吸系统疾病，以慢性炎症为主要特征，而中性粒细胞弹性蛋白酶作为一种重要炎性蛋白酶，它能消化、水解细胞外基质和上皮连接结构，损害气道上皮完整性、损伤肺组织，在该病的演变进展过程中具有重要意义。文章对两者的相关性进行综述与探讨，为中性粒细胞弹性蛋白酶抑制剂作为慢性阻塞性肺疾病临床用药提供新视野及一定理论基础。
Abstract:
Chronic obstructive pulmonary disease is a common multiple respiratory disease, which is mainly characterized by chronic inflammation. As an important inflammatory protease, neutrophil elastase can digest and hydrolyze extracellular matrix and epithelial junction structure, damage the integrity of airway epithelium, and damage lung tissue, which is of great significance in the evolution and progress of the disease. This article reviews and discusses the correlation between them, providing a new perspective and a certain theoretical basis for the use of neutrophil elastase inhibitors as clinical drugs for chronic obstructive pulmonary disease.

参考文献/References:

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备注/Memo

备注/Memo:
【收稿日期】2022-11-07 【基金项目】国家自然科学基金地区科学基金（81760853）；国家宋庆龄基金会（2018MZFT-028）。 【作者简介】胡晓玲（1995－），女，广西中医药大学在读硕士研究生，研究方向为中西医结合防治呼吸系统疾病。 【通信作者】陈斯宁（1963－），女，广西中医药大学附属瑞康医院主任医师，教授，研究方向为中西医结合防治呼吸系统疾病。
更新日期/Last Update: 2023-03-30