[1]马 华.放射性核素骨显像技术与PSA联合检测在前列腺癌骨转移中的临床运用价值[J].大众科技,2023,25(1):82-85.
 Clinical Application Value of Radionuclide Bone Imaging Combined with PSA in Detecting Bone Metastasis of Prostate Cancer[J].Popular Science & Technology,2023,25(1):82-85.
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放射性核素骨显像技术与PSA联合检测在 前列腺癌骨转移中的临床运用价值()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
25
期数:
2023年1
页码:
82-85
栏目:
医药与卫生
出版日期:
2023-01-20

文章信息/Info

Title:
Clinical Application Value of Radionuclide Bone Imaging Combined with PSA in Detecting Bone Metastasis of Prostate Cancer
作者:
马 华 
(淮安市肿瘤医院,江苏 淮安 223200)
关键词:
放射性核素显像技术血清前列腺特异性抗原(PSA)联合检查临床运用价值
Keywords:
radionuclide imaging technology serum prostate specific antigen (PSA) joint examination clinical application value
文献标志码:
A
摘要:
目的:分析放射性核素骨显像技术与PSA联合检测在前列腺癌骨转移中的临床运用价值。方法:对淮安市肿瘤医院2019年1月至2022年1月间诊治的40例前列腺癌患者同时进行放射性核素骨显像技术及血清前列腺特异性抗原(PSA)联合检测的结果进行回顾性分析。结果:放射性核素显像技术显示骨转移38例,阳性率占95%。38例骨转移病例中,发生在中轴骨转移较多,主要部位以胸、腰椎为主,有20例,占骨转移例数的52.63%;骨盆次之,有13例,占34.21%;胸骨、四肢及四肢带骨、肋骨、颅骨转移占比较少,有5例,占13.16%,多部位骨转移灶有23例,占60.53%;PSA检测显示其浓度越高其放射性核素显示比例越高,两者呈现正相关,PSA<20 μg/L患者,骨转移灶显示率较低。结论:PSA血清检测结果大于或等于20 μg/L患者,应该进行放射性核素全身骨显像检查,为后续治疗方案的制定和对疾病发展趋势的研判提供有效的临床参考依据。
Abstract:
Objective: To analyze the clinical application value of radionuclide bone imaging combined with PSA in detecting bone metastasis of prostate cancer. Methods: The results of radionuclide bone imaging and PSA combined detection in 40 patients with prostate cancer diagnosed and treated in Huaian Cancer Hospital from January 2019 to January 2022 were retrospectively analyzed. Results: Radionuclide imaging showed 38 cases of bone metastasis, and the positive rate was 95%. Among the 38 cases of bone metastases, more bone metastasis occurred in the middle axis bone, mainly in the thoracic and lumbar vertebrae, 20 cases, accounting for 52.63% of the cases of bone metastasis followed by the pelvis, 13 cases, accounting for 34.21% limbs and limb girdle bones, ribs, and skull metastasis accounted for less, 5 cases, accounting for 13.16%, and 23 cases of multi-site bone metastasis, accounting for 60.53% PSA detection shows that the higher the concentration is, the higher the radionuclide display proportion is, and the two are positively correlated, PSA<20 μ In g/L patients, the display rate of bone metastasis was low. Conclusion: Patients with PSA serum test results greater than or equal to 20 μg/L should undergo radionuclide whole body bone imaging examination, which provides an effective clinical reference for the formulation of subsequent treatment plans and the judgment of disease development trends.

参考文献/References:

[1] 赵泽豫. 比较全身MRI、CT和放射性核素骨显像对乳腺癌骨转移治疗反应的评估[J]. 国际医学放射学杂志,2021,44(1): 112. [2] 邹波,钟建,晏文强. 放射性核素骨显像联合血清PSA、fPSA、ALP及BAP在评价内分泌疗法治疗前列腺癌疗效中的应用价值[J]. 中国肿瘤外科杂志,2018,10(6): 393-395. [3] 廖华强. Meta分析比较~(18)FDG-PET、CT、MRI及放射性核素骨显像对骨转移的诊断[J]. 国际医学放射学杂志,2012,35(1): 101. [4] 付立武. F-FDG PETCT最大标准摄取值联合血清PSA检查在前列腺癌诊断中的应用价值[J]. 临床医学,2021,41(2): 30-31. [5] 高中山,贾志斌,曾祥高,等. ~(18)F-FDG PETCT最大SUVmax与PSA在前列腺癌诊治中的相关性研究[J]. 中国CT和MRI杂志,2018,16(8): 122-123,152. [6] 张建伟,王洪伟,许科,等. 放射性核素骨显像联合磁共振全身弥散加权成像诊断乳腺癌骨转移的价值[J]. 中国实用医刊,2021,48(21): 66-70.

备注/Memo

备注/Memo:
【收稿日期】2022-10-12 【作者简介】马华(1975-),男,江苏淮安人,淮安市肿瘤医院核医学科副主任医师,研究方向为核医学诊断及治疗。
更新日期/Last Update: 2023-03-30