[1]何文军.高压氧辅助治疗小儿病毒性脑炎的疗效观察分析[J].大众科技,2022,24(07):37-40.
　Observation and Analysis of Curative Effect of Hyperbaric Oxygen Adjuvant Therapy for Children with Viral Encephalitis[J].Popular Science & Technology,2022,24(07):37-40.
点击复制

高压氧辅助治疗小儿病毒性脑炎的 疗效观察分析()
分享到：

《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
24
期数:
2022年07
页码:
37-40
栏目:
医药与卫生
出版日期:
2022-07-20

文章信息/Info

Title:
Observation and Analysis of Curative Effect of Hyperbaric Oxygen Adjuvant Therapy for Children with Viral Encephalitis
作者:
何文军　
（广西宾阳县人民医院，广西 南宁 530400）
关键词:
小儿病毒性脑炎; 高压氧; 总有效率; 临床症状消失时间; 生化指标
Keywords:
pediatric viral encephalitis hyperbaric oxygen total effective rate disappearance time of clinical symptoms biochemical index
文献标志码:
A
摘要:
目的：分析小儿病毒性脑炎治疗中高压氧辅助治疗效果。方法：选取广西宾阳县人民医院2020年1月至2021年12月收治的39例小儿病毒性脑炎患儿为研究对象，利用随机数字表法进行分组。对照组20例采取常规治疗，观察组19例加用高压氧辅助治疗，比较两组总有效率、临床症状（发热、呕吐、头痛、昏迷、惊厥）消失时间、生化指标（血清神经元特异烯醇化酶、神经生长因子）、后遗症（语言障碍、智力障碍、感觉障碍）总发生率差异。结果：观察组的总有效率高于对照组，临床症状消失时间短于对照组，后遗症发生率与治疗后的生化指标低于对照组，差异有统计学意义（P＜0.05）。结论：高压氧辅助治疗小儿病毒性脑炎疗效确切，值得推广。
Abstract:
Objective: To analyze the effect of adjuvant hyperbaric oxygen therapy in the treatment of children with viral encephalitis. Methods: A total of 39 children with viral encephalitis who were admitted to Binyang County Peoples Hospital from January 2020 to December 2021 were selected as the research objects, and the random number table method was used to group them. 20 cases in the control group were given routine treatment, while 19 cases in the observation group were additionally given hyperbaric oxygen adjuvant therapy. The total effective rate, clinical symptoms (fever, vomiting, headache, coma, convulsion) disappearance time, biochemical indexes (serum neuron specific enolase, nerve growth factor) and the total incidence of sequelae (language disorder, intellectual disorder, sensory disorder) were compared between the two groups. Results: The total effective rate of the observation group was higher than that of the control group, the disappearance time of clinical symptoms was shorter than that of the control group, the incidence of sequelae and biochemical indexes after treatment were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion: The effect of hyperbaric oxygen adjuvant therapy on children with viral encephalitis is definite and worthy of promotion.

参考文献/References:

[1] 吕丹，舒艳梅，朱琴. 阿昔洛韦联合高压氧治疗小儿急性病毒性脑炎的临床效果[J]. 临床合理用药杂志，2021，14(11): 36-37，41. [2] 李仁君，任小玲，冉亚林. 高压氧治疗对病毒性脑炎患儿脑神经功能、Th17/Treg细胞水平以及TLR2/NF-κB通路的影响[J]. 中华航海医学与高气压医学杂志，2021，28(4): 469-474. [3] 余明英，刘勤，彭丹，等. 高压氧辅助治疗对病毒性脑炎患儿疗效及其作用机制[J]. 中华航海医学与高气压医学杂志，2021，28(5): 607-611. [4] 贲友凤，丁晓芳，袁伯稳. 高压氧辅助治疗联合功能康复训练对病毒性脑炎患儿临床症状、血清学指标及脑电图变化的影响[J]. 中华航海医学与高气压医学杂志，2021，28(2): 183-186，196. [5] 张保霞，张晓，徐瑞. 短程甲基强的松龙冲击联合高压氧对重症病毒性脑炎患儿血清S100B蛋白、NGF水平及预后的影响[J]. 中国免疫学杂志，2019，35(21): 2638-2643.

备注/Memo

备注/Memo:
【收稿日期】2022-05-21 【作者简介】何文军（1975－），男，广西宾阳人，广西宾阳县人民医院主治医师，在职硕士研究生，从事小儿内科治疗等相关工作。
更新日期/Last Update: 2022-08-10