[1]农吉晓 黄慕槿 唐勇华 刘雅玲.中医药治疗视网膜静脉阻塞的用药规律研究[J].大众科技,2022,24(01):115-119.
　Study on the Medication Law of Traditional Chinese Medicine in the Treatment of Retinal Vein Occlusion[J].Popular Science & Technology,2022,24(01):115-119.
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中医药治疗视网膜静脉阻塞的用药规律研究()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
24
期数:
2022年01
页码:
115-119
栏目:
医药与卫生
出版日期:
2022-01-20

文章信息/Info

Title:
Study on the Medication Law of Traditional Chinese Medicine in the Treatment of Retinal Vein Occlusion
作者:
农吉晓1 黄慕槿1 唐勇华2 刘雅玲1　
（1.广西中医药大学研究生学院，广西 南宁 530000； 2.广西中医药大学附属瑞康医院，广西 南宁 530000）
关键词:
视网膜静脉阻塞; 数据挖掘; 中药; 用药规律; 聚类分析
Keywords:
retinal vein occlusion data mining traditional Chinese medicine medication law cluster analysis
文献标志码:
A
摘要:
目的：采用数据挖掘技术探讨中医药治疗视网膜静脉阻塞的用药规律。方法：检索中国知网（CNKI）、万方（Wanfang）、维普（VIP）三大数据库，检索时间限定为2000年1月1日至2020年12月31日之前，设定相关主题或关键词进行检索，使用Note Express建立文献数据库，阅读全文并根据纳入及排除标准提取相关数据录入Microsoft Excel，再采用SPSS 26.0软件分析记录药物的使用频次、药性、功效、性味归经、聚类分析。通过IBM SPSS Modeler 18.0软件高频药物进行关联规则分析。结果：最终筛选出符合条件的核心文献112篇，纳入方剂共163首，共涉及中药174味。其中高频中药有33味（频次≥15次），依次为当归、赤芍、地黄、川芎、丹参等。药物功效以补虚药、止血药及清热药为主；其药性以寒为主；药味多甘苦。脏腑归经多为肝经、肺经、心经。当归为所有药物中使用频次最多的药物，在RVO治疗中占据重要位置。关联分析中支持度最强的组合是“桃仁-红花”，核心药物聚类分析出5首新方。结论：RVO中药治疗的总体用药特点以活血通络、理气化瘀为基本大法，辅以止血、利水渗湿、益气等治法。
Abstract:
Objective: To explore the medication law of traditional Chinese medicine in the treatment of retinal vein occlusion by data mining technology. Methods: The three databases of CNKI, Wanfang and VIP were searched. The retrieval time was limited from January 1, 2000 to December 31, 2020. The relevant topics or keywords were set for retrieval. The document database was established by Note Express, the full text was read, and the relevant data were extracted according to the inclusion and exclusion criteria and entered into Microsoft Excel, Then SPSS 26.0 software was used to analyze and record the drug use frequency, drug properties, efficacy, sexual and flavor meridians and cluster analysis. The association rules of high-frequency drugs were analyzed by IBM SPSS Modeler 18.0 software. Results: Finally, 112 core literature meeting the conditions were screened out, including 163 prescriptions, involving 174 flavors of traditional Chinese medicine. There were 33 high-frequency traditional Chinese medicines(frequency≥15 times), followed by Angelica sinensis, red peony, Rehmannia glutinosa, Ligusticum chuanxiong, Salvia miltiorrhiza, etc. The drug efficacy is mainly tonic, hemostatic and antipyretic drugs its medicinal properties are mainly cold the medicine tastes bitter and sweet. Zang Fu meridians are mostly liver meridians, lung meridians and heart meridians. Angelica sinensis is the most frequently used drug among all drugs and occupies an important position in RVO treatment. The combination with the strongest support in association analysis is "peach kernel-safflower", and five new prescriptions are obtained by cluster analysis of core drugs. Conclusion: The overall medication characteristics of RVO traditional Chinese medicine treatment are based on the basic principles of activating blood and dredging collaterals, regulating qi and resolving stasis, supplemented by the therapies of hemostasis, draining water and draining dampness, and tonifying qi.

参考文献/References:

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备注/Memo

备注/Memo:
【收稿日期】2021-10-11 【作者简介】农吉晓，女（壮族），广西中医药大学研究生学院在读硕士研究生，研究方向为中医五官科。
更新日期/Last Update: 2022-04-20