[1]张　涛　胡展瑞　李　锋　廖民霞　覃明媚　李珊珊.腕踝针对减少癌性爆发痛次数及改善疼痛介质与炎症因子水平的影响[J].大众科技,2021,23(10):113-116.
　Effect of Wrist ankle Acupuncture on Reducing the Number of Cancer Outbreak Pain and Improving the Levels of Pain Mediators and Inflammatory Factors[J].Popular Science & Technology,2021,23(10):113-116.
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腕踝针对减少癌性爆发痛次数及改善疼痛介质与炎症因子水平的影响()
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《大众科技》[ISSN:1008-1151/CN:45-1235/N]

卷:
23
期数:
2021年10
页码:
113-116
栏目:
医药与卫生
出版日期:
2021-10-20

文章信息/Info

Title:
Effect of Wrist ankle Acupuncture on Reducing the Number of Cancer Outbreak Pain and Improving the Levels of Pain Mediators and Inflammatory Factors
作者:
张　涛　胡展瑞　李　锋　廖民霞　覃明媚　李珊珊
（梧州市中医医院，广西 梧州 543002）
关键词:
腕踝针; 难治性癌痛; 癌性爆发痛; 改善; 疼痛介质; 炎症因子
Keywords:
wrist ankle acupuncture refractory cancer paincancer outbreak pain improve pain mediatorsinflammatory factors
文献标志码:
A
摘要:
目的：探究腕踝针治疗难治性癌痛对减少癌性爆发痛（Breakthrough cancer pain, BTcP）次数及改善疼痛介质与炎症因子水平的影响。方法：将2019年1月至2021年2月在广西梧州市中医医院接受治疗的103例难治性癌痛患者视为研究对象，以随机数字表法分为两组，甲组采用癌症三阶梯止痛法治疗，乙组在甲组基础上行腕踝针治疗，对比两组临床疗效、治疗前后不同时间点BTcP次数、视觉模拟量表（visual analogue scale，VAS）评分、炎症因子、疼痛介质指标水平。结果：乙组治疗总有效率高于甲组，治疗第2 d、第6 d与第10 d时的VAS评分、肿瘤坏死因子-α（Tumor necrosis factor-α，TNF-α）、白细胞介素-6（Interleukin-6，IL-6）、白细胞介素-1β（Interleukin-1β，IL-1β）水平、5-羟色胺（5-hydroxytryptamine，5-HT）、P物质（Substance P，SP）、前列腺素E2（Prostaglandin E2，PGE2）水平低于甲组，BTcP次数少于甲组（P＜0.05）。结论：腕踝针治疗难治性癌痛能够有效缓解疼痛，减少BTcP次数，改善机体炎症因子水平与疼痛介质。
Abstract:
Objective: To explore the effect of wrist ankle acupuncture in the treatment of refractory cancer pain on reducing the number of breakthrough cancer pain (BTcP) and improving the levels of pain mediators and inflammatory factors. Methods: 103 patients with refractory cancer pain treated in Guangxi Wuzhou traditional Chinese medicine hospital from January 2019 to February 2021 were regarded as the research objects. They were randomly divided into two groups. Group A was treated with cancer three-step analgesic method, and group B was treated with wrist ankle acupuncture on the basis of group A. The clinical efficacy, BTcP times at different time points before and after treatment, visual analogue scale (VAS) score, inflammatory factors and pain mediators were compared between the two groups. Results: The total effective rate of group B was higher than that of group A, the VAS score and tumor necrosis factor at the 2nd, 6th and 10th days of tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), interleukin-1β (IL-1 β), 5-hydroxytryptamine (5-HT), substance P (SP) and prostaglandin E2 (PGE2) were lower than group A, and BTcP frequency was lower than group A (P<0.05). Conclusion: wrist ankle acupuncture can effectively relieve pain, reduce BTcP times and improve the level of inflammatory factors and pain medium in the body.

参考文献/References:

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　Research Progress of Traditional Chinese and Western Medicine in the Treatment of Refractory Cancer Pain[J].Popular Science & Technology,2021,23(10):71.

备注/Memo

备注/Memo:
【收稿日期】2021-08-11 【作者简介】张涛（1987－），女，广西梧州人，梧州市中医医院针炙科主治医师，研究方向为中医针炙推拿学。
更新日期/Last Update: 2022-01-28